Expression of the human microRNA miR 29a in an Indian cohort of HIV patients

نویسندگان

  • Rakesh Dey
  • Kartik Soni
  • Shanmugam Saravanan
  • Pachamuthu Balakrishnan
  • Vikram Kumar
  • Vinod Scaria
  • Beena Pillai
  • Suniti Solomon
  • Samir K Brahmachari
چکیده

Background The events during host virus interaction pave the way to differential outcomes in HIV-1 disease progression rates. We have earlier shown that HIV-1Nef gene harbors target sites for the human microRNA, miRNA 29a/b. Over expression of miR 29a/b could reduce virus levels by targeting the Nef gene. We hypothesized that differential expression of the microRNA maybe a protective factor in AIDS progression.

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2014